Ukraine's largest metals plant, ArcelorMittal, began production of naphthalene that was halted by missile strikes.
The factory in Kariboi Rog is moved to "cold shutdown" mode.
"Our current assessment is that safe operation is not possible while the war continues. After the end of the war, when the conditions allow it, we will start a dialogue with the government of Ukraine and re-examine whether it is possible to resume the activity safely and sustainably", say the company's management.
Earlier, the Cariboo Rogue City Council asked Indian billionaire Lakshmi Mittal not to close the factory, which employs about 17,000 people.
The industry says that all Ukrainian metal factories have already been destroyed by shelling.