Rubio may resign ahead of the 2028 presidential election According to The Independent, the US Secretary of State is considering leaving the Trump administration to distance himself from the war with Iran and prepare to fight for the Republican nomination. It is said that the vice president J. Dee Vance is his main potential opponent. The newspaper's sources believe that the relationship with the Trump administration could harm Rubio's presidential ambitions. The White House and the State Department called the publication baseless. Rubio himself has not publicly announced plans to resign.