Threefold increase in gene expression with a new nanocarrier in breast cancer models.
Mariam Joldran - IRNA reporter.
By combining strontium sulfite nanoparticles and lipid nanoparticles, researchers have designed a new hybrid carrier for the delivery of messenger RNA (mRNA) molecules. In cell experiments, this system increased the expression of the tumor suppressor gene p53 threefold and reduced tumor growth in a mouse model of breast cancer.