Summary of carbon monoxide poisoning. An acute pathological condition resulting from the inhalation of carbon monoxide (CO), a colorless and odorless gas. CO binds to erythrocyte hemoglobin to form carboxyhemoglobin; The affinity of hemoglobin for CO is 200-300 times higher than for oxygen. oxygen transport to tissues is disturbed, severe hypoxia develops; The brain and heart muscle are the most sensitive. Without timely treatment, irreversible damage and death may occur. Acizol. specific medicine; The active ingredient is zinc bisvinyl dithiocarbamate. Mechanism: competitive displacement of CO from its association with hemoglobin. Acizole binds to hemoglobin, forming a complex with a higher affinity for the protein than CO; The CO-hemoglobin bond is disrupted and CO is released. Some of the hemoglobin is temporarily converted to methemoglobin, which binds the released CO to form carboxy-methemoglobin. The complexes are unstable: acizol-hemoglobin and carboxymethamoglobin complex break down, hemoglobin is returned to a functionally active form, CO is excreted unchanged through the lungs. The therapeutic effect is a rapid reduction in the level of carboxyhemoglobin in the blood, reducing hypoxia, preventing damage to vital organs and reducing the risk of late neurological complications. request. only in emergency medical treatment by medical staff; Self-care is not acceptable. Release form: 6% solution for intramuscular injection, ampoules 1 ml. Adults - 1 ml (60 mg) intramuscularly, again after 60-90 minutes. For children - individually, usually 0.5-1 mg/kg body weight per injection. Maximum effectiveness - given as early as possible after poisoning. Acizol does not replace resuscitation measures: immediate removal to fresh air if necessary, artificial respiration and supply of pure oxygen, hyperbaric oxygenation.

Summary of carbon monoxide poisoning. An acute pathological condition resulting from the inhalation of carbon monoxide (CO), a colorless and odorless gas. CO binds to erythrocyte hemoglobin to form carboxyhemoglobin; The affinity of hemoglobin for CO is 200-300 times higher than for oxygen. oxygen transport to tissues is disturbed, severe hypoxia develops; The brain and heart muscle are the most sensitive. Without timely treatment, irreversible damage and death may occur. Acizol. specific medicine; The active ingredient is zinc bisvinyl dithiocarbamate. Mechanism: competitive displacement of CO from its association with hemoglobin. Acizole binds to hemoglobin, forming a complex with a higher affinity for the protein than CO; The CO-hemoglobin bond is disrupted and CO is released. Some of the hemoglobin is temporarily converted to methemoglobin, which binds the released CO to form carboxy-methemoglobin. The complexes are unstable: acizol-hemoglobin and carboxymethamoglobin complex break down, hemoglobin is returned to a functionally active form, CO is excreted unchanged through the lungs. The therapeutic effect is a rapid reduction in the level of carboxyhemoglobin in the blood, reducing hypoxia, preventing damage to vital organs and reducing the risk of late neurological complications. request. only in emergency medical treatment by medical staff; Self-care is not acceptable. Release form: 6% solution for intramuscular injection, ampoules 1 ml. Adults - 1 ml (60 mg) intramuscularly, again after 60-90 minutes. For children - individually, usually 0.5-1 mg/kg body weight per injection. Maximum effectiveness - given as early as possible after poisoning. Acizol does not replace resuscitation measures: immediate removal to fresh air if necessary, artificial respiration and supply of pure oxygen, hyperbaric oxygenation.